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Glucosamine is a natural compound found in cartilage — the tough tissue that cushions joints.
In supplement form, glucosamine is harvested from shells of shellfish or made in a lab. There are several forms of glucosamine, including glucosamine sulfate, glucosamine hydrochloride and N-acetyl glucosamine. These supplements aren't considered interchangeable.
People use glucosamine sulfate orally to treat a painful condition caused by the inflammation, breakdown and eventual loss of cartilage (osteoarthritis).
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